Glanzmann thrombasthenia

Red blood cell clot retraction : possible compensative mechanism for patients with Glanzmann thrombasthenia ?

红细胞收缩：血小板无力症的可能代偿机制？

Retrospective study on 45 infants with glanzmann thrombasthenia Objective To study clinical features and laboratory examination of Chinese child patients with Glanzmann thrombasthenia ( GT ) .

小儿血小板无力症45例临床及实验室资料分析目的分析总结血小板无力症（GT）患儿的临床特征和实验室资料。

Phenotype and genotype diagnosis in five Chinese pedigrees with Glanzmann thrombasthenia

五个遗传性血小板无力症家系的表型和基因型诊断

αⅱ bA477P ( A446P ): A New Mutation Found in Patients with Glanzmann Thrombasthenia

αⅡbA477P（A446P）&发生于血小板无力症患者的新突变

ObjectiveTo elucidate the genetic defects in patients with Glanzmann thrombasthenia ( GT ) and set up the experimental basis for further exploring the pathogenesis of GT .

明确血小板无力症患者的基因缺陷，为进一步探讨其发病机理奠定实验基础。

Objective To identify the mutation of integrin αⅱ b β 3 in four probands with Glanzmann thrombasthenia through phenotype and gene diagnosis and investigate molecular pathogenesis of GT .

目的：对4例遗传性血小板无力症（GT）先证者及其父母进行表型和基因诊断，确定基因突变的位点，并探讨其分子发病机制。

Methods A female patient was diagnosed as Glanzmann thrombasthenia through the platelet count , the platelet morphology and distribution on the blood film , the bleeding time assay , the coagulation profiles and the platelet aggregation test .

方法：通过血小板计数、血涂片观察血小板、出血时间测定、凝血象检查和血小板聚集试验进行表型诊断；

Flow cytometric diagnosis of Glanzmann 's thrombasthenia

流式细胞术诊断血小板无力症

Glanzmann 's thrombasthenia is a bleeding disorder caused by qualitative and / or quantitative difects of platelet membrane glycoprotein ( GP ) II b / III . complex .

血小板无力症是由于血小板膜糖蛋白（GP）Ⅱb/Ⅲa：复合物质和/或量的异常所致的一种出血性疾病。